Drug Information
Drug General Information | |||||
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Drug ID |
D0O7LU
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Former ID |
DIB018932
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Drug Name |
AZD3463
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Synonyms |
AZD-3463; CS-1382; HY-15609; KB-154896
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [542681] | ||
Structure |
Download2D MOL |
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Formula |
C24H25ClN6O
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InChI |
InChI=1S/C24H25ClN6O/c1-32-22-12-16(31-10-8-15(26)9-11-31)6-7-21(22)29-24-28-14-19(25)23(30-24)18-13-27-20-5-3-2-4-17(18)20/h2-7,12-15,27H,8-11,26H2,1H3,(H,28,29,30)
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InChIKey |
GCYIGMXOIWJGBU-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | mRNA of Insulin-like growth factor 1 receptor | Target Info | Inhibitor | [543490] | |
ALK tyrosine kinase receptor | Target Info | Inhibitor | [543509] | ||
KEGG Pathway | Ras signaling pathway | ||||
Rap1 signaling pathway | |||||
HIF-1 signaling pathway | |||||
FoxO signaling pathway | |||||
Oocyte meiosis | |||||
Endocytosis | |||||
PI3K-Akt signaling pathway | |||||
AMPK signaling pathway | |||||
Focal adhesion | |||||
Adherens junction | |||||
Signaling pathways regulating pluripotency of stem cells | |||||
Long-term depression | |||||
Ovarian steroidogenesis | |||||
Progesterone-mediated oocyte maturation | |||||
Pathways in cancer | |||||
Transcriptional misregulation in cancer | |||||
Proteoglycans in cancer | |||||
Glioma | |||||
Prostate cancer | |||||
Melanomahsa05223:Non-small cell lung cancer | |||||
WikiPathways | Senescence and Autophagy in Cancer | ||||
Insulin Signaling | |||||
Endochondral Ossification | |||||
Focal Adhesion | |||||
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | |||||
Apoptosis | |||||
Signaling Pathways in Glioblastoma | |||||
TSH signaling pathway | |||||
MicroRNAs in cardiomyocyte hypertrophyWP2848:Differentiation Pathway | |||||
References | |||||
Ref 543490 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1801). | ||||
Ref 543509 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1839). |
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