Drug Information
Drug General Information | |||||
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Drug ID |
D0O7GU
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Former ID |
DAP001026
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Drug Name |
Palifermin
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Synonyms |
Kepivance; Kepivance (TN); Palifermin (USAN/INN)
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Therapeutic Class |
Antimucositis Agents
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Formula |
C721H1142N202O204S9
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CAS Number |
CAS 162394-19-6
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PubChem Substance ID | |||||
SuperDrug ATC ID |
V03AF08
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Target and Pathway | |||||
Target(s) | Fibroblast growth factor receptor 2 | Target Info | Binder | [537352] | |
NetPath Pathway | IL1 Signaling Pathway | ||||
PANTHER Pathway | FGF signaling pathway | ||||
Pathway Interaction Database | FGF signaling pathway | ||||
Reactome | Activated point mutants of FGFR2 | ||||
WikiPathways | Regulation of Actin Cytoskeleton | ||||
Ectoderm Differentiation | |||||
Hair Follicle Development: Organogenesis (Part 2 of 3) | |||||
Hair Follicle Development: Induction (Part 1 of 3) | |||||
Cardiac Hypertrophic Response | |||||
Signaling Pathways in Glioblastoma | |||||
Neural Crest Differentiation | |||||
Signaling by FGFR | |||||
MicroRNAs in cardiomyocyte hypertrophy | |||||
Angiogenesis | |||||
References | |||||
Ref 536838 | Emerging drugs for chemotherapy-induced mucositis. Expert Opin Emerg Drugs. 2008 Sep;13(3):511-22. | ||||
Ref 541990 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6954). |
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