Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0O3KA
|
||||
Former ID |
DNCL002337
|
||||
Drug Name |
RG7602
|
||||
Indication | Lymphoma [ICD9: 202.8, 208.9; ICD10:C81-C86] | Discontinued in Phase 1 | [549282] | ||
Company |
Array BioPharma; Roche
|
||||
Target and Pathway | |||||
Target(s) | Serine/threonine-protein kinase Chk1 | Target Info | Modulator | [550475] | |
Pathway Interaction Database | Fanconi anemia pathway | ||||
p73 transcription factor network | |||||
ATR signaling pathway | |||||
Circadian rhythm pathway | |||||
p53 pathway | |||||
Reactome | Activation of ATR in response to replication stress | ||||
Processing of DNA double-strand break ends | |||||
Presynaptic phase of homologous DNA pairing and strand exchange | |||||
G2/M DNA damage checkpoint | |||||
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | |||||
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | |||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.