Drug Information
Drug General Information | |||||
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Drug ID |
D0O3EP
|
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Former ID |
DNCL002921
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Drug Name |
SRT2379
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Indication | Type 2 diabetes [ICD9: 250; ICD10:E11] | Phase 1 | [522863] | ||
Company |
Sirtris
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Target and Pathway | |||||
Target(s) | NAD-dependent deacetylase sirtuin-1 | Target Info | Modulator | [550534] | |
PANTHER Pathway | p53 pathway | ||||
Pathway Interaction Database | p73 transcription factor network | ||||
Signaling events mediated by HDAC Class III | |||||
E2F transcription factor network | |||||
HIF-2-alpha transcription factor network | |||||
Signaling events mediated by HDAC Class I | |||||
FoxO family signaling | |||||
Regulation of Androgen receptor activity | |||||
Regulation of retinoblastoma protein | |||||
References |
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