Drug Information
Drug General Information | |||||
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Drug ID |
D0O0JB
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Former ID |
DIB007070
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Drug Name |
PSMA-targeted tubulysin B conjugates
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Synonyms |
DUPA-TubH III; DUPA-tubulysin III; EC-1069; PSMA-targeted tubulysin B conjugates (prostate cancer); PSMA-targeted tubulysin B conjugates (prostate cancer), Endocyte/Purdue University
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Indication | Prostate cancer [ICD9: 185; ICD10:C61] | Phase 1 | [549705] | ||
Company |
Endocyte
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Structure |
Download2D MOL |
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Canonical SMILES |
c1(nc(sc1)[C@@H](C[C@@H](N(C(=O)[C@@H](NC(=O)[C@@H]1N(C<br />)CCCC1)[C@H](CC)C)COC(=O)CC(C)C)C(C)C)OC(=O)C)C(=O)N[C@<br />H](C[C@@H](C(=O)NNC(=O)OCCSSC[C@H](NC(=O)[C@@H](NC(=O)[<br />C@@H](NC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)N[C@H](C(=O)O)C<br />CC(=O)O)C(=O)O)C(=O)O)CC(=O)O)Cc1ccccc1)C(=O)O)C)Cc1ccc<br />(cc1)O
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Target and Pathway | |||||
Target(s) | Glutamate carboxypeptidase II | Target Info | Modulator | [530072] | |
NetPath Pathway | TCR Signaling Pathway | ||||
TNFalpha Signaling Pathway | |||||
WikiPathways | One Carbon Metabolism | ||||
References |
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