Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0NQ7I
|
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| Former ID |
DNC005191
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| Drug Name |
SPONGIADIOXIN A
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C12H4Br4O3
|
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| Canonical SMILES |
C1=C(C=C2C(=C1Br)OC3=C(O2)C(=CC(=C3Br)Br)O)Br
|
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| InChI |
1S/C12H4Br4O3/c13-4-1-6(15)10-8(2-4)18-11-7(17)3-5(14)9(16)12(11)19-10/h1-3,17H
|
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| InChIKey |
SSCRQJOLSHUSSG-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 15-lipoxygenase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Resolvin D biosynthesis | ||||
| Lipoxin biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Linoleic acid metabolism | |||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PANTHER Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | ||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | |||||
| References | |||||
| REF 1 | J Med Chem. 2004 Jul 29;47(16):4060-5.Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. | ||||
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