Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0N4OZ
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| Former ID |
DNC003044
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| Drug Name |
Epothilone D
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| Drug Type |
Small molecular drug
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| Indication | Breast cancer [ICD9: 174, 175; ICD10:C50] | Discontinued in Phase 2 | [547385] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C27H41NO5S
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| Canonical SMILES |
CC1CCCC(=CCC(OC(=O)CC(C(C(=O)C(C1O)C)(C)C)O)C(=CC2=CSC(<br />=N2)C)C)C
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| InChI |
1S/C27H41NO5S/c1-16-9-8-10-17(2)25(31)19(4)26(32)27(6,7)23(29)14-24(30)33-22(12-11-16)18(3)13-21-15-34-20(5)28-21/h11,13,15,17,19,22-23,25,29,31H,8-10,12,14H2,1-7H3/b16-11-,18-13+/t17-,19+,22-,23-,25-/m0/s1
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| InChIKey |
XOZIUKBZLSUILX-GIQCAXHBSA-N
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| CAS Number |
CAS 189453-10-9
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| PubChem Compound ID | |||||
| PubChem Substance ID |
14194, 527930, 535887, 829612, 7887334, 10300127, 12015122, 14835263, 14859543, 42305233, 57404838, 71825098, 74380482, 78256894, 103306072, 104638620, 126623096, 126681411, 137253077, 142409108, 152258664, 160647501, 172087013, 179316795, 186014466, 198969321, 223393856, 223662786, 223718736, 223882697, 226396415, 247008306, 252215362, 252307186, 252434232
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| Target and Pathway | |||||
| Target(s) | Tubulin beta | Target Info | Inhibitor | [551393] | |
| PANTHER Pathway | Cytoskeletal regulation by Rho GTPase | ||||
| Huntington disease | |||||
| References | |||||
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