Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0N3XT
|
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| Former ID |
DNC006030
|
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| Drug Name |
BREQUINAR
|
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| Drug Type |
Small molecular drug
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C23H15F2NO2
|
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| InChI |
InChI=1S/C23H15F2NO2/c1-13-21(23(27)28)18-12-16(24)10-11-20(18)26-22(13)15-8-6-14(7-9-15)17-4-2-3-5-19(17)25/h2-12H,1H3,(H,27,28)
|
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| InChIKey |
PHEZJEYUWHETKO-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
604688, 833552, 5141941, 7886333, 8185015, 11407783, 14779823, 43114774, 46504783, 46515644, 47960438, 50065413, 57313868, 78503079, 96099826, 103216339, 104311590, 126421111, 128915510, 134343235, 135030617, 137220339, 141792749, 152200612, 152343569, 152343570, 160825160, 160966637, 162011531, 162150672, 162201837, 163092469, 163384428, 163840377, 163884586, 170558732, 171063036, 174531766, 178103978, 179151469, 198976397, 202565961, 204383117, 223402609, 223536769, 226433170, 241168208, 242060369, 250121679
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| Target and Pathway | |||||
| Target(s) | Dihydroorotate dehydrogenase | Target Info | Modulator | ||
| KEGG Pathway | Pyrimidine metabolism | ||||
| Metabolic pathways | |||||
| PANTHER Pathway | De novo pyrimidine ribonucleotides biosythesis | ||||
| PathWhiz Pathway | Pyrimidine Metabolism | ||||
| Reactome | Pyrimidine biosynthesis | ||||
| WikiPathways | Metabolism of nucleotides | ||||
| References | |||||
| Ref 542429 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7406). | ||||
| Ref 544729 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000749) | ||||
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