Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0N1TP
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| Former ID |
DAP000211
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| Drug Name |
Paricalcitol
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| Synonyms |
Paracalcin; Zemplar; Abbott brand of paricalcitol; Paricalcitol [USAN]; Ab 122358; ABT-358; Zemplar (TN); Paricalcitol (USAN/INN); Paricalcitol, 19-nor-(OH)2-vitD2, paracalcin; (1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol; (1R,3R,7E)-17beta-[(2R,3E,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-9,10-secoestra-5,7-diene-1,3-diol; (1alpha.3beta,7E,22E)-19-Nor-9,10-secoergosta-5,7,22-triene-1,3,25-triol; (7E,22E)-19-Nor-9,10-secoergosta-5,7,22-triene-1alpha,3beta,25-triol; 19-Nor-1,25-(OH)2D2; 19-Nor-1-alpha,25-dihydroxyvitamin D2; 19-Nor-1alpha,25-dihydroxyvitamin D2; 19-Nor-9,10-secoergosta-5,7,22-triene-1,3,25-triol,(1alpha,3beta,7E,22E)
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Parasympathomimetics
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| Company |
Abbott Laboratories
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| Structure |
|
Download2D MOL |
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| Formula |
C27H44O3
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| InChI |
InChI=1S/C27H44O3/c1-18(8-9-19(2)26(3,4)30)24-12-13-25-21(7-6-14-27(24,25)5)11-10-20-15-22(28)17-23(29)16-20/h8-11,18-19,22-25,28-30H,6-7,12-17H2,1-5H3/b9-8+,21-11+/t18-,19+,22-,23-,24-,25+,27-/m1/s1
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| InChIKey |
BPKAHTKRCLCHEA-UBFJEZKGSA-N
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| CAS Number |
CAS 131918-61-1
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| PubChem Compound ID | |||||
| PubChem Substance ID |
10327, 7847993, 8616515, 11528763, 12015105, 14758016, 14880085, 39290016, 46505780, 53788968, 56352881, 57358016, 76588451, 85300892, 92719080, 93166488, 103770605, 104179021, 109692762, 113854558, 124894114, 126621096, 126645826, 126648293, 126670318, 134337526, 135035651, 135651536, 137005143, 137541249, 143496453, 144116337, 144206540, 152164212, 152238013, 152258860, 160647709, 160964249, 162176752, 164764064, 165238229, 175267449, 179149809, 184607566, 184811940, 196108673, 223657699, 224327771, 226395789, 250184670
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| ChEBI ID |
ChEBI:7931
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| SuperDrug ATC ID |
H05BX02
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| Target and Pathway | |||||
| Target(s) | Vitamin D receptor | Target Info | Agonist | [537420] | |
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PANTHER Pathway | Vitamin D metabolism and pathway | ||||
| References | |||||
| Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
| Ref 539837 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2791). | ||||
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