Drug Information

Drug General Information
Drug ID
D0N0VW
Former ID
DIB002437
Drug Name
IDN-5174
Synonyms
Camptothecin analogs (anticancer); IDN-5174; Camptothecin analogs (anticancer), Indena
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Investigative [543672]
Company
Indena SpA
Structure
Download
2D MOL

3D MOL
Canonical SMILES
n12c(c3c([C@H]2N=[N+]=[N-])cc2c(n3)cccc2)cc2c(c1=O)COC(<br />=O)[C@]2(O)CC
Target and Pathway
Target(s) Toposisomerase-1 Target Info Inhibitor [543672]
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway DNA replication
Pathway Interaction Database Caspase Cascade in Apoptosis
WikiPathways Integrated Pancreatic Cancer Pathway
References
Ref 543672(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2636).
Ref 543672(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2636).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.