Drug Information

Drug General Information
Drug ID
D0MH1K
Former ID
DNC012777
Drug Name
SC-55634
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551257]
Structure
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2D MOL

3D MOL
Formula
C28H35N7O
Canonical SMILES
CCCCC1=CN(C(=O)N1CC2=CN=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C5C<br />(CCCC5C)C
InChI
1S/C28H35N7O/c1-4-5-11-22-18-35(26-19(2)9-8-10-20(26)3)28(36)34(22)17-21-14-15-25(29-16-21)23-12-6-7-13-24(23)27-30-32-33-31-27/h6-7,12-16,18-20,26H,4-5,8-11,17H2,1-3H3,(H,30,31,32,33)/t19-,20+,26?
InChIKey
GBXQWPCVQAHRBS-NJEHHLDASA-N
PubChem Compound ID
9935096
Target and Pathway
Target(s) Type-2 angiotensin II receptor Target Info Inhibitor [551257]
KEGG Pathway Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Renin-angiotensin system
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways ACE Inhibitor Pathway
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 551257N1-sterically hindered 2H-imidazol-2-one angiotensin II receptor antagonists: The conversion of surmountable antagonists to insurmountable antagonists, Bioorg. Med. Chem. Lett. 3(6):1055-1060 (1993).
Ref 551257N1-sterically hindered 2H-imidazol-2-one angiotensin II receptor antagonists: The conversion of surmountable antagonists to insurmountable antagonists, Bioorg. Med. Chem. Lett. 3(6):1055-1060 (1993).

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