TTD | Drug: D0M9FC

Drug General Information
Drug ID	D0M9FC
Former ID	DNC010683
Drug Name	(R)-3-(2-naphthamido)-4-m-tolylbutanoic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530771]
Structure		Download 2D MOL 3D MOL
Formula	C22H21NO3
Canonical SMILES	CC1=CC(=CC=C1)CC(CC(=O)O)NC(=O)C2=CC3=CC=CC=C3C=C2
InChI	1S/C22H21NO3/c1-15-5-4-6-16(11-15)12-20(14-21(24)25)23-22(26)19-10-9-17-7-2-3-8-18(17)13-19/h2-11,13,20H,12,14H2,1H3,(H,23,26)(H,24,25)/t20-/m1/s1
InChIKey	LDUFWTJAUGDLSR-HXUWFJFHSA-N
PubChem Compound ID	46884013
Target and Pathway
Target(s)	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Target Info	Inhibitor	[530771]
KEGG Pathway	RIG-I-like receptor signaling pathway
Pathway Interaction Database	p73 transcription factor network
	C-MYC pathway
	PDGFR-beta signaling pathway
	p53 pathway
Reactome	ISG15 antiviral mechanism
Reactome	Negative regulators of RIG-I/MDA5 signaling
WikiPathways	ISG15 antiviral mechanism
WikiPathways	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
References
Ref 530771	Bioorg Med Chem Lett. 2010 Apr 1;20(7):2210-4. Epub 2010 Feb 14.Structure-based design of novel human Pin1 inhibitors (II).
Ref 530771	Bioorg Med Chem Lett. 2010 Apr 1;20(7):2210-4. Epub 2010 Feb 14.Structure-based design of novel human Pin1 inhibitors (II).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information