Drug Information
Drug General Information | |||||
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Drug ID |
D0M3XR
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Former ID |
DNCL002892
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Drug Name |
MK-3102
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Synonyms |
Omarigliptin
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Drug Type |
Small molecular drug
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Company |
Merck
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Structure |
Download2D MOL |
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Formula |
C17H20F2N4O3S
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InChI |
InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17-/m1/s1
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InChIKey |
MKMPWKUAHLTIBJ-ISTRZQFTSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Dipeptidyl peptidase IV | Target Info | Modulator | [532717] | |
KEGG Pathway | Protein digestion and absorption | ||||
NetPath Pathway | IL2 Signaling Pathway | ||||
TGF_beta_Receptor Signaling Pathway | |||||
References | |||||
Ref 524091 | ClinicalTrials.gov (NCT01703208) A Study to Assess Cardiovascular Outcomes Following Treatment With MK-3102 in Participants With Type 2 Diabetes Mellitus (MK-3102-018). U.S. National Institutes of Health. | ||||
Ref 543109 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8402). |
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