Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0LH1A
|
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| Former ID |
DNC000441
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| Drug Name |
CL 385319
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| Drug Type |
Small molecular drug
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C15H18F4N2O
|
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| Canonical SMILES |
C1CCN(CC1)CCNC(=O)C2=CC(=CC(=C2)F)C(F)(F)F
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| InChI |
1S/C15H18F4N2O/c16-13-9-11(8-12(10-13)15(17,18)19)14(22)20-4-7-21-5-2-1-3-6-21/h8-10H,1-7H2,(H,20,22)
|
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| InChIKey |
VSXLWIDIFZEXHE-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Hemagglutinin | Target Info | Inhibitor | [535252], [535454], [536931], [538146] | |
| References | |||||
| Ref 535252 | An approach to the identification of potent inhibitors of influenza virus fusion using parallel synthesis methodology. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2393-6. | ||||
| Ref 535454 | Novel stachyflin derivatives from Stachybotrys sp. RF-7260. Fermentation, isolation, structure elucidation and biological activities. J Antibiot (Tokyo). 2002 Mar;55(3):239-48. | ||||
| Ref 536931 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17736-41. Epub 2008 Nov 12. | ||||
| Ref 538146 | Inhibition of influenza A virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin. J Virol. 1999 Jan;73(1):140-51. | ||||
| Ref 535252 | An approach to the identification of potent inhibitors of influenza virus fusion using parallel synthesis methodology. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2393-6. | ||||
| Ref 535454 | Novel stachyflin derivatives from Stachybotrys sp. RF-7260. Fermentation, isolation, structure elucidation and biological activities. J Antibiot (Tokyo). 2002 Mar;55(3):239-48. | ||||
| Ref 536931 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17736-41. Epub 2008 Nov 12. | ||||
| Ref 538146 | Inhibition of influenza A virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin. J Virol. 1999 Jan;73(1):140-51. | ||||
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