Drug Information
Drug General Information | |||||
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Drug ID |
D0L5UO
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Former ID |
DCL000102
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Drug Name |
Darapladib
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Synonyms |
SB 480848; Darapladib (USAN)
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Drug Type |
Small molecular drug
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Company |
GlaxoSmithKline
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Structure |
Download2D MOL |
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Formula |
C36H38F4N4O2S
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InChI |
InChI=1S/C36H38F4N4O2S/c1-3-42(4-2)20-21-43(22-25-8-12-27(13-9-25)28-14-16-29(17-15-28)36(38,39)40)33(45)23-44-32-7-5-6-31(32)34(46)41-35(44)47-24-26-10-18-30(37)19-11-26/h8-19H,3-7,20-24H2,1-2H3
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InChIKey |
WDPFJWLDPVQCAJ-UHFFFAOYSA-N
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CAS Number |
CAS 356057-34-6
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PubChem Compound ID | |||||
PubChem Substance ID |
14912817, 17397748, 24212669, 51238364, 57373852, 103163821, 104017492, 123055336, 131311864, 134338793, 135195691, 137124696, 140342334, 144115884, 162201858, 163620709, 163686026, 170502612, 175426322, 178103307, 179150370, 185974990, 188932643, 190861993, 198984335, 223385373, 223704897, 228826696, 242060329, 243523950, 249737039, 251971364, 252155042, 252215249, 252451735, 252810760
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Target and Pathway | |||||
Target(s) | Phospholipase A2 | Target Info | Modulator | [552985] | |
BioCyc Pathway | Phospholipases | ||||
Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
WikiPathways | Glycerophospholipid biosynthesis | ||||
References | |||||
Ref 541801 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6696). | ||||
Ref 547463 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016591) |
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