Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0L3JI
|
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| Former ID |
DCL000898
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| Drug Name |
NGD 94-1
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| Synonyms |
Ngd-94-1; 2-Phenyl-4(5)-((4-(2-pyrimidinyl)-piperazin-1-yl)methyl)imidazole dimaleate; 2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]piperazin-1-yl]pyrimidine; 2-{4-[(2-phenyl-1h-imidazol-4-yl)methyl]piperazin-1-yl}pyrimidine
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| Drug Type |
Small molecular drug
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| Company |
Schering-Plough
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| Structure |
|
Download2D MOL |
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| Formula |
C18H20N6
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| InChI |
InChI=1S/C18H20N6/c1-2-5-15(6-3-1)17-21-13-16(22-17)14-23-9-11-24(12-10-23)18-19-7-4-8-20-18/h1-8,13H,9-12,14H2,(H,21,22)
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| InChIKey |
OTVQCHUIPJYASM-UHFFFAOYSA-N
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| CAS Number |
CAS 113082-98-7
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7980118, 10260910, 14752667, 14801399, 33510547, 47954537, 48404542, 57396204, 79440170, 85209204, 103114526, 103318571, 103857974, 103952294, 113444874, 117522070, 126451647, 128861023, 134339350, 134339963, 135165781, 135650712, 136351236, 137074326, 137111890, 142282999, 143160218, 162805282, 163121853, 172876490, 178100334, 179293732, 204363639, 232578952, 233957622, 241376369, 246752231, 249617821, 252157171
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| Target and Pathway | |||||
| Target(s) | D(4) dopamine receptor | Target Info | Antagonist | [536463] | |
| References | |||||
| Ref 536463 | The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31. | ||||
| Ref 543342 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 979). | ||||
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