| Drug General Information |
| Drug ID |
D0L2MU
|
| Former ID |
DNC004993
|
| Drug Name |
7-Bromo-2-(4-hydroxy-phenyl)-benzofuran-5-ol
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C14H9BrO3
|
| Canonical SMILES |
C1=CC(=CC=C1C2=CC3=CC(=CC(=C3O2)Br)O)O
|
| InChI |
1S/C14H9BrO3/c15-12-7-11(17)5-9-6-13(18-14(9)12)8-1-3-10(16)4-2-8/h1-7,16-17H
|
| InChIKey |
UBYHIUUMRHTEFF-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Estrogen receptor |
Target Info |
Inhibitor |
[1]
|
|---|
| Estrogen receptor beta |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Estrogen signaling pathway
|
|
Prolactin signaling pathway
|
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Thyroid hormone signaling pathway
|
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Endocrine and other factor-regulated calcium reabsorption
|
|
Proteoglycans in cancerhsa04915:Estrogen signaling pathway
|
|
NetPath Pathway
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FSH Signaling Pathway
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EGFR1 Signaling Pathway
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RANKL Signaling Pathway
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Pathway Interaction Database
|
Regulation of nuclear SMAD2/3 signaling
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Signaling events mediated by HDAC Class II
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Plasma membrane estrogen receptor signaling
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LKB1 signaling events
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Regulation of Telomerase
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ATF-2 transcription factor network
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AP-1 transcription factor network
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FOXM1 transcription factor network
|
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Validated nuclear estrogen receptor alpha network
|
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Signaling mediated by p38-alpha and p38-beta
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FOXA1 transcription factor networker_nongenomic_pathway:Plasma membrane estrogen receptor signaling
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Validated nuclear estrogen receptor beta network
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Reactome
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Nuclear signaling by ERBB4
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Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
|
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WikiPathways
|
Estrogen signaling pathway
|
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Nuclear Receptors Meta-Pathway
|
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Estrogen Receptor Pathway
|
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Signaling by ERBB4
|
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JAK/STAT
|
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Integrated Pancreatic Cancer Pathway
|
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Leptin signaling pathway
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miR-targeted genes in muscle cell - TarBase
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Integrated Breast Cancer Pathway
|
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Nuclear ReceptorsWP706:SIDS Susceptibility Pathways
|
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Ovarian Infertility Genes
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|
Nuclear Receptors
|
| References |
| REF 1 | Bioorg Med Chem Lett. 2004 Oct 4;14(19):4925-9.7-Substituted 2-phenyl-benzofurans as ER beta selective ligands. |
|---|
