Drug Information

Drug General Information
Drug ID
D0KR5K
Former ID
DIB007855
Drug Name
Capravirine
Synonyms
AG-1549; S-1153; NNRTI (HIV infection), Pfizer
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Phase 1 [521433]
Company
Shionogi & Co Ltd
Structure
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2D MOL

3D MOL
Formula
C20H20Cl2N4O2S
Canonical SMILES
c1(n(c(nc1C(C)C)COC(=O)N)Cc1ccncc1)Sc1cc(cc(c1)Cl)Cl
CAS Number
CAS 178979-85-6
PubChem Compound ID
1783
Target and Pathway
Target(s) HIV reverse transcriptase Target Info Inhibitor [527112]
References
Ref 521433ClinicalTrials.gov (NCT00002214) Phase I Trial of S-1153 in Patients With HIV Infection. U.S. National Institutes of Health.
Ref 527112Metabolism and excretion of capravirine, a new non-nucleoside reverse transcriptase inhibitor, alone and in combination with ritonavir in healthy volunteers. Drug Metab Dispos. 2004 Jul;32(7):689-98.

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