Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0KG3R
|
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| Former ID |
DNAP001688
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| Drug Name |
Rivaroxaban
|
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| Synonyms |
XARELTO (TN)
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| Drug Type |
Small molecular drug
|
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| Company |
Bayer HealthCare Pharmaceuticals; Johnson & Johnson Pharmaceutical Research & Development
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C19H18ClN3O5S
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| InChI |
InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1
|
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| InChIKey |
KGFYHTZWPPHNLQ-AWEZNQCLSA-N
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| CAS Number |
CAS 366789-02-8
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| PubChem Compound ID | |||||
| PubChem Substance ID |
14856850, 15279667, 22395270, 24164597, 45622373, 46513422, 51091428, 52936629, 56373953, 57373622, 71825413, 87225360, 87557471, 91615930, 93580340, 99444948, 103469795, 109693118, 126659499, 126666963, 134342998, 134358083, 135213418, 135684125, 136375511, 136920411, 137128738, 139479843, 152258851, 152344334, 160645892, 160647701, 160969514, 162172236, 164045359, 164194090, 164824489, 165245531, 170498903, 171578894, 172091286, 174477515, 175266472, 175427064, 175610897, 177748765, 178103004, 180189087, 185985285, 198991713
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| ChEBI ID |
ChEBI:68579
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| SuperDrug ATC ID |
B01AF01
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| Target and Pathway | |||||
| Target(s) | Coagulation factor Xa | Target Info | Modulator | [551871] | |
| KEGG Pathway | Complement and coagulation cascades | ||||
| PANTHER Pathway | Blood coagulation | ||||
| Pathway Interaction Database | Beta2 integrin cell surface interactions | ||||
| PathWhiz Pathway | Coagulation | ||||
| Reactome | Extrinsic Pathway of Fibrin Clot Formation | ||||
| Intrinsic Pathway of Fibrin Clot Formation | |||||
| Common Pathway of Fibrin Clot Formation | |||||
| Gamma-carboxylation of protein precursors | |||||
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
| References | |||||
| Ref 531783 | 2011 FDA drug approvals. Nat Rev Drug Discov. 2012 Feb 1;11(2):91-4. | ||||
| Ref 541524 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6388). | ||||
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