Drug Information
Drug General Information | |||||
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Drug ID |
D0K8NR
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Former ID |
DCL000425
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Drug Name |
AMG 386
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Drug Type |
Small molecular drug
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Company |
Amgen
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Structure |
Download2D MOL |
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Formula |
Na
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Canonical SMILES |
[Na]
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InChI |
1S/Na
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InChIKey |
KEAYESYHFKHZAL-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
5326610, 8146756, 10534514, 15170295, 15237733, 24845275, 24848128, 24853383, 24854694, 24855921, 24857014, 24857016, 24868737, 24871915, 24881721, 24886151, 24886235, 24888697, 33088985, 39384005, 50046431, 50074094, 53788965, 57362018, 57647078, 57648086, 57652275, 57652326, 77905220, 83620210, 88826695, 114148349, 117376386, 125809647, 126675963, 131325865, 134339053, 134339153, 134339154, 134339155, 134339359, 134339385, 134339536, 134339884, 134340144, 134987874, 134988506, 137102243, 137156482, 139072878
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Target and Pathway | |||||
Target(s) | Angiopoietin-2 | Target Info | Modulator | [1572591] | |
Angiopoietin-1 | Target Info | Modulator | [1572591] | ||
PANTHER Pathway | AngiogenesisP00005:Angiogenesis | ||||
References | |||||
Ref 523327 | ClinicalTrials.gov (NCT01281254) TRINOVA-2: Trebananib in Ovarian Cancer-2. U.S. National Institutes of Health. | ||||
Ref 543118 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8414). |
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