Drug Information

Drug General Information
Drug ID
D0K8MP
Former ID
DAP001235
Drug Name
Permethrin
Synonyms
Ambush; PerFoam; Transpermethrin; Acticin Cream; Elimite Cream; Nix Cream Rinse; Transpermethrin [ISO];FMC 35171; NRDC 146; NRDC 148; PS758_SUPELCO; Permethrin (isomers); Permethrin (isomers) solution; Permethrine,c&t; Trans-(+-)-Permethrin; [3-(phenyloxy)phenyl]methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate; (+)-CIS-PERMETHRIN; (+)-trans-Permethrin; (+-)-cis-Fmc 33297; (+-)-cis-Permethrin; (+-)-trans-Permethrin; (3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate; (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate; 1RS,cis-Permethrin; 1RS-trans-Permethrin; 3-Phenoxybenzyle (1RS)-cis, trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylate; 3-phenoxybenzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
Drug Type
Small molecular drug
Indication Infections with sarcoptes scabiei [ICD9: 133; ICD10:B86] Approved [538286], [551871]
Therapeutic Class
Insecticides
Structure
Download
2D MOL

3D MOL
Formula
C21H20Cl2O3
Canonical SMILES
CC1(C(C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C
InChI
1S/C21H20Cl2O3/c1-21(2)17(12-18(22)23)19(21)20(24)25-13-14-7-6-10-16(11-14)26-15-8-4-3-5-9-15/h3-12,17,19H,13H2,1-2H3
InChIKey
RLLPVAHGXHCWKJ-UHFFFAOYSA-N
CAS Number
CAS 52645-53-1
PubChem Compound ID
40326
PubChem Substance ID
5646900, 8176555, 10525033, 10525292, 10526594, 14854178, 17395388, 24868001, 24869115, 24869349, 24871630, 24899290, 26675675, 26754479, 26754481, 26754482, 26754483, 26754484, 29215320, 29215321, 34706112, 46505374, 47207113, 48415484, 48421679, 48425983, 49833360, 49959692, 49959696, 50109850, 56310674, 56312325, 56314259, 57260102, 57260103, 57288423, 57312421, 57650455, 57650562, 74717839, 85088539, 85189547, 91696064, 103559256, 104334065, 117452446, 118783839, 121362319, 124800250, 124892140
ChEBI ID
ChEBI:34911
SuperDrug ATC ID
P03AC04
SuperDrug CAS ID
cas=052645531
Target and Pathway
Target(s) Sodium channel Target Info Blocker [535876]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 538286FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074806.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 535876In vitro assays for repellents and deterrents for ticks: differing effects of products when tested with attractant or arrestment stimuli. Med Vet Entomol. 2003 Dec;17(4):370-8.

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