Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0K8LN
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| Former ID |
DNC005486
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| Drug Name |
1-Chloro-4-(1-phenyl-cyclohexanesulfonyl)-benzene
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [527542] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C18H19ClO2S
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| Canonical SMILES |
C1CCC(CC1)(C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)Cl
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| InChI |
1S/C18H19ClO2S/c19-16-9-11-17(12-10-16)22(20,21)18(13-5-2-6-14-18)15-7-3-1-4-8-15/h1,3-4,7-12H,2,5-6,13-14H2
|
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| InChIKey |
XMYNJSLMUBGZIQ-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Presenilin 1 | Target Info | Inhibitor | [527542] | |
| Presenilin 2 | Target Info | Inhibitor | [527542] | ||
| NetPath Pathway | Notch Signaling Pathway | ||||
| Reactome | Degradation of the extracellular matrixR-HSA-1251985:Nuclear signaling by ERBB4 | ||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| NOTCH2 Activation and Transmission of Signal to the Nucleus | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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