TTD | Drug: D0K5XL

Drug General Information
Drug ID	D0K5XL
Former ID	DNC006948
Drug Name	ADS-103293
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528581]
Structure		Download 2D MOL 3D MOL
Formula	C21H21ClN4O2
Canonical SMILES	CC1=NC(=NC2=C1C=C(C=C2)NC(=O)COC3=CC=CC=C3Cl)N4CCCC4
InChI	1S/C21H21ClN4O2/c1-14-16-12-15(24-20(27)13-28-19-7-3-2-6-17(19)22)8-9-18(16)25-21(23-14)26-10-4-5-11-26/h2-3,6-9,12H,4-5,10-11,13H2,1H3,(H,24,27)
InChIKey	XIYWAMFWFFFEQL-UHFFFAOYSA-N
PubChem Compound ID	11440885
Target and Pathway
Target(s)	Melanin-concentrating hormone receptor 1	Target Info	Inhibitor	[528581]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528581	Bioorg Med Chem Lett. 2007 Mar 1;17(5):1403-7. Epub 2006 Dec 2.Quinazoline and benzimidazole MCH-1R antagonists.
Ref 528581	Bioorg Med Chem Lett. 2007 Mar 1;17(5):1403-7. Epub 2006 Dec 2.Quinazoline and benzimidazole MCH-1R antagonists.

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Drug Information