| Drug General Information |
| Drug ID |
D0K4PY
|
| Former ID |
DNC008191
|
| Drug Name |
LIQUIRTIGENIN
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C15H12O4
|
| Canonical SMILES |
C1C(OC2=C(C1=O)C=CC(=C2)O)C3=CC=C(C=C3)O
|
| InChI |
1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2/t14-/m0/s1
|
| InChIKey |
FURUXTVZLHCCNA-AWEZNQCLSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Xanthine dehydrogenase/oxidase |
Target Info |
Inhibitor |
[1]
|
|---|
| Cytochrome P450 19 |
Target Info |
Inhibitor |
[2]
|
|
BioCyc Pathway
|
Purine nucleotides degradation
|
|
Urate biosynthesis/inosine 5'-phosphate degradation
|
|
Guanosine nucleotides degradation
|
|
Adenosine nucleotides degradation
|
|
Retinoate biosynthesis IIPWY-7305:Superpathway of steroid hormone biosynthesis
|
|
Estradiol biosynthesis II
|
|
Estradiol biosynthesis I
|
|
KEGG Pathway
|
Purine metabolism
|
|
Caffeine metabolism
|
|
Drug metabolism - other enzymes
|
|
Metabolic pathways
|
|
Peroxisomehsa00140:Steroid hormone biosynthesis
|
|
Ovarian steroidogenesis
|
|
NetPath Pathway
|
FSH Signaling Pathway
|
|
PANTHER Pathway
|
Adenine and hypoxanthine salvage pathway
|
|
Purine metabolismP02727:Androgen/estrogene/progesterone biosynthesis
|
|
PathWhiz Pathway
|
Caffeine Metabolism
|
|
Purine MetabolismPW000045:Androgen and Estrogen Metabolism
|
|
Reactome
|
Purine catabolismR-HSA-211976:Endogenous sterols
|
|
WikiPathways
|
Oxidative Stress
|
|
Effects of Nitric Oxide
|
|
Metabolism of nucleotides
|
|
Selenium Micronutrient NetworkWP702:Metapathway biotransformation
|
|
Tryptophan metabolism
|
|
Oxidation by Cytochrome P450
|
|
Ovarian Infertility Genes
|
|
Metabolism of steroid hormones and vitamin D
|
|
FSH signaling pathway
|
|
Integrated Breast Cancer Pathway
|
|
Phase 1 - Functionalization of compounds
|
| References |
| REF 1 | Inhibition of cow's milk xanthine oxidase by flavonoids. J Nat Prod. 1988 Mar-Apr;51(2):345-8. |
|---|
| REF 2 | Bioorg Med Chem. 2008 Sep 15;16(18):8466-70. Epub 2008 Aug 19.Screening of herbal constituents for aromatase inhibitory activity. |
|---|
