Drug Information

Drug General Information
Drug ID
D0K2EX
Former ID
DIB019345
Drug Name
compound 21
Synonyms
C21
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531967], [541963]
Structure
Download
2D MOL
Formula
C23H29N3O4S2
InChI
InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)
InChIKey
XTEOJPUYZWEXFI-UHFFFAOYSA-N
PubChem Compound ID
9804984
PubChem Substance ID
14761106, 24113010, 44840981, 77916801, 103458615, 104043405, 178103500, 223894285, 226865504, 244486876, 252160614
Target and Pathway
Target(s) Type-2 angiotensin II receptor Target Info Agonist [531967]
KEGG Pathway Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Renin-angiotensin system
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways ACE Inhibitor Pathway
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 531967Compound 21 induces vasorelaxation via an endothelium- and angiotensin II type 2 receptor-independent mechanism. Hypertension. 2012 Sep;60(3):722-9.
Ref 541963(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6918).
Ref 531967Compound 21 induces vasorelaxation via an endothelium- and angiotensin II type 2 receptor-independent mechanism. Hypertension. 2012 Sep;60(3):722-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.