Drug General Information
Drug ID	D0K1NM
Former ID	DNC002719
Drug Name	1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551374]
Structure		Download 2D MOL 3D MOL
Formula	C15H20N2O
PubChem Compound ID	20541332
Target and Pathway
Target(s)	Heme oxygenase	Target Info	Inhibitor	[551374]
BioCyc Pathway	Heme degradation
KEGG Pathway	Porphyrin and chlorophyll metabolism
	HIF-1 signaling pathway
	Mineral absorption
	MicroRNAs in cancer
Pathway Interaction Database	Validated transcriptional targets of AP1 family members Fra1 and Fra2
	HIF-1-alpha transcription factor network
PathWhiz Pathway	Porphyrin Metabolism
Reactome	Iron uptake and transport
WikiPathways	Oxidative Stress
	Transcriptional activation by NRF2
	NRF2 pathway
	Nuclear Receptors Meta-Pathway
	miR-targeted genes in squamous cell - TarBase
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
	miR-targeted genes in leukocytes - TarBase
	miR-targeted genes in epithelium - TarBase
References
Ref 551374	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
Ref 551374	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.

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