Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0J9PG
|
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| Former ID |
DIB018787
|
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| Drug Name |
AH6809
|
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| Synonyms |
AH 6809; AH-6809
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [539195] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C17H14O5
|
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| InChI |
InChI=1S/C17H14O5/c1-9(2)21-11-4-5-12-15(8-11)22-14-6-3-10(17(19)20)7-13(14)16(12)18/h3-9H,1-2H3,(H,19,20)
|
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| InChIKey |
AQFFXPQJLZFABJ-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7443493, 10238505, 11113635, 14825137, 29300337, 47434900, 47731300, 50064693, 53790735, 57339507, 75107704, 85208944, 85788105, 103806142, 104408395, 117546890, 123220340, 125334269, 126602127, 127443469, 135074174, 135649910, 135698615, 136345201, 136351284, 162022587, 162249868, 162516594, 179150333, 184825517, 210274683, 210280316, 227401076, 241181815, 241377434, 242132245, 250136929, 251962951, 252457259, 252477541
|
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| Target and Pathway | |||||
| Target(s) | Prostaglandin E2 receptor, EP1 subtype | Target Info | Antagonist | [534595] | |
| Prostaglandin E2 receptor EP3 subtype | Target Info | Antagonist | [525673] | ||
| Prostaglandin E2receptor, EP2 subtype | Target Info | Antagonist | [525673] | ||
| Prostaglandin D2 receptor | Target Info | Antagonist | [525673] | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Pathways in cancerhsa04020:Calcium signaling pathway | |||||
| cAMP signaling pathway | |||||
| Regulation of lipolysis in adipocytes | |||||
| Pathways in cancerhsa04024:cAMP signaling pathway | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| Renin secretion | |||||
| Pathways in cancerhsa04080:Neuroactive ligand-receptor interaction | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | PI3 kinase pathway | ||||
| Pathway Interaction Database | Thromboxane A2 receptor signaling | ||||
| PathWhiz Pathway | Intracellular Signalling Through PGD2 receptor and Prostaglandin D2 | ||||
| References | |||||
| Ref 525673 | The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta. 2000 Jan 17;1483(2):285-93. | ||||
| Ref 534595 | Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. Eur J Pharmacol. 1997 Dec 11;340(2-3):227-41. | ||||
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