Drug Information

Drug General Information
Drug ID
D0J4GO
Former ID
DAP000601
Drug Name
Dichlorphenamide
Synonyms
Antidrasi; Barastonin; Daranide; Dasanide; Dichlofenamide; Dichlorophenamide; Dichlorphenamid; Diclofenamid; Diclofenamida; Diclofenamide; Diclofenamidum; Glafco; Glajust; Glaucol; Glauconide; Glaumid; Oratrol; Dichlorphenamide [BAN]; Llorens Brand of Dichlorphenamide; Merck Brand of Dichlorphenamide; CB 8000; I7A; Daranide (TN); Dichlorophenamide (DCP); Dichlorphenamide (USP); Diclofenamida [INN-Spanish]; Diclofenamidum [INN-Latin]; Diclofenamide (JP15/INN); 1,3-Disulfamoyl-4,5-dichlorobenzene; 1,3-Disulfamyl-4,5-dichlorobenzene; 3,4-Dichloro-5-sulfamylbenzenesulfonamide; 4,5-Dichloro-1,3-benzenedisulfonamide; 4,5-Dichloro-1,3-disulfamoylbenzene; 4,5-Dichloro-benzene-1,3-disulfonic acid diamide; 4,5-Dichloro-m-benzenedisulfonamide; 4,5-dichlorobenzene-1,3-disulfonamide
Drug Type
Small molecular drug
Indication Chronic glaucoma [ICD9: 365; ICD10:H40-H42] Approved [538446], [541889]
Therapeutic Class
Antiglaucomic Agents
Structure
Download
2D MOL

3D MOL
Formula
C6H6Cl2N2O4S2
InChI
InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14)
InChIKey
GJQPMPFPNINLKP-UHFFFAOYSA-N
CAS Number
CAS 120-97-8
PubChem Compound ID
3038
PubChem Substance ID
9662, 5394315, 7847584, 8151933, 10321980, 10505613, 11112264, 11466837, 11467957, 11486334, 14898599, 26717464, 29222184, 46505039, 46511453, 47291265, 47662454, 47662455, 48185135, 48415882, 49698651, 49879995, 50100403, 50920273, 53812947, 56463645, 57321571, 61013445, 85787355, 87350459, 92125643, 92729678, 99375170, 99444419, 103164700, 103914449, 104253501, 104302345, 118050517, 118307481, 121363314, 124757623, 124801457, 125164427, 125659078, 126652477, 126687904, 126729448, 127963474, 134337892
SuperDrug ATC ID
S01EC02
SuperDrug CAS ID
cas=000120978
Target and Pathway
Target(s) Carbonic anhydrase I Target Info Modulator [556264]
KEGG Pathway Nitrogen metabolism
Pathway Interaction Database C-MYB transcription factor network
PathWhiz Pathway Gastric Acid Production
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Reversible hydration of carbon dioxide
WikiPathways Reversible Hydration of Carbon Dioxide
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 538446FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 011366.
Ref 541889(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6807).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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