Drug General Information
Drug ID	D0J2NS
Former ID	DNC000223
Drug Name	Anti-D
Drug Type	Small molecular drug
Indication	Idiopathic thrombocytopenic purpura [ICD9: 287.31; ICD10:D69.3]		Investigative	[536737]
Structure		Download 2D MOL 3D MOL
Formula	C6H14ClNO5
Canonical SMILES	C(C1C(C(C(C(O1)O)N)O)O)O.Cl
InChI	1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6-;/m1./s1
InChIKey	QKPLRMLTKYXDST-OCOFDJSDSA-N
CAS Number	CAS 66-84-2
PubChem Compound ID	9859210
PubChem Substance ID	14822544, 24152610, 26611758, 26679579, 29204185, 45281506, 57373577, 75124350, 92123957, 124637435, 134339710, 144075063, 162093875, 226410542
SuperDrug ATC ID	M01AX05
SuperDrug CAS ID	cas=003416248
Target and Pathway
Target(s)	D(2) dopamine receptor	Target Info	Antagonist	[536737]
KEGG Pathway	Rap1 signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Alcoholism
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Dopamine receptor mediated signaling pathway
	Nicotine pharmacodynamics pathway
Reactome	Dopamine receptors
	G alpha (i) signalling events
WikiPathways	Hypothetical Network for Drug Addiction
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Genes and (Common) Pathways Underlying Drug Addiction
	GPCR ligand binding
	GPCR downstream signaling
	Nicotine Activity on Dopaminergic Neurons
References
Ref 536737	Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54.
Ref 536737	Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54.

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