Drug Information

Drug General Information
Drug ID
D0J0RV
Former ID
DCL000552
Drug Name
Larotaxel
Synonyms
Benzenepropanoic acid; PNU 100940; XRP 9881; XRP9881
Drug Type
Small molecular drug
Indication Pancreatic cancer; Bladder cancer [ICD9: 188; ICD10:C25, C67] Discontinued in Phase 3 [546774]
Company
Sanofi-Aventis
Structure
Download
2D MOL

3D MOL
Formula
C45H53NO14
Canonical SMILES
CC1=C2C(C(=O)C34CC3CC5C(C4C(C(C2(C)C)(CC1OC(=O)C(C(C6=C<br />C=CC=C6)NC(=O)OC(C)(C)C)O)O)OC(=O)C7=CC=CC=C7)(CO5)OC(=<br />O)C)OC(=O)C
InChI
1S/C45H53NO14/c1-23-29(57-39(52)33(49)32(26-15-11-9-12-16-26)46-40(53)60-41(4,5)6)21-45(54)37(58-38(51)27-17-13-10-14-18-27)35-43(36(50)34(56-24(2)47)31(23)42(45,7)8)20-28(43)19-30-44(35,22-55-30)59-25(3)48/h9-18,28-30,32-35,37,49,54H,19-22H2,1-8H3,(H,46,53)/t28-,29+,30-,32+,33-,34-,35+,37+,43-,44+,45-/m1/s1
InChIKey
DXOJIXGRFSHVKA-BZVZGCBYSA-N
CAS Number
CAS 156294-36-9
PubChem Compound ID
6918260
PubChem Substance ID
14767168, 16732220, 23950815, 43529643, 78087543, 135261536, 139108290, 164761536, 198989487, 221678787, 226496387, 247981801, 252110039
Target and Pathway
Target(s) Tubulin Target Info Inhibitor [549823]
References
Ref 546774Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010227)
Ref 549823Pharma & Vaccines. Product Development Pipeline. April 29 2009.

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