Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0IZ4Z
|
||||
Former ID |
DNC008889
|
||||
Drug Name |
3-[4-(4-Hydroxyphenyl)-1,3-oxazol-2-yl]phenol
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Discovery agent | Investigative | [529504] | ||
Structure |
Download2D MOL |
||||
Formula |
C15H11NO3
|
||||
Canonical SMILES |
C1=CC(=CC(=C1)O)C2=NC(=CO2)C3=CC=C(C=C3)O
|
||||
InChI |
1S/C15H11NO3/c17-12-6-4-10(5-7-12)14-9-19-15(16-14)11-2-1-3-13(18)8-11/h1-9,17-18H
|
||||
InChIKey |
NOWYSMIMXQPTPC-UHFFFAOYSA-N
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Estradiol 17 beta-dehydrogenase 1 | Target Info | Inhibitor | [529504] | |
NetPath Pathway | FSH Signaling Pathway | ||||
PANTHER Pathway | Androgen/estrogene/progesterone biosynthesis | ||||
PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
References | |||||
Ref 529504 | Bioorg Med Chem. 2008 Jun 15;16(12):6423-35. Epub 2008 May 3.Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases. | ||||
Ref 529504 | Bioorg Med Chem. 2008 Jun 15;16(12):6423-35. Epub 2008 May 3.Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.