Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0IE6Z
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| Former ID |
DNC001133
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| Drug Name |
Platelet factor 4 (PF-4)
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [540502] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C71H126N16O17
|
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| Canonical SMILES |
CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O<br />)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C<br />(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC1=CC=C(C=C1<br />)O)NC(=O)C(CC(C)C)N
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| InChI |
1S/C71H126N16O17/c1-11-43(9)58(87-70(102)59(44(10)12-2)86-65(97)51(24-16-20-34-75)78-61(93)48(21-13-17-31-72)79-68(100)55(38-45-25-27-46(89)28-26-45)82-60(92)47(76)35-40(3)4)69(101)81-50(23-15-19-33-74)62(94)77-49(22-14-18-32-73)63(95)83-54(37-42(7)8)67(99)84-53(36-41(5)6)66(98)80-52(29-30-57(90)91)64(96)85-56(39-88)71(103)104/h25-28,40-44,47-56,58-59,88-89H,11-24,29-39,72-76H2,1-10H3,(H,77,94)(H,78,93)(H,79,100)(H,80,98)(H,81,101)(H,82,92)(H,83,95)(H,84,99)(H,85,96)(H,86,97)(H,87,102)(H,90,91)(H,103,104)/t43-,44-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,58-,59-/m0/s1
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| InChIKey |
SVIMOXOHMCOIRM-UVKYVJJHSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Fibroblast growth factor receptor 2 | Target Info | Inhibitor | [535131] | |
| NetPath Pathway | IL1 Signaling Pathway | ||||
| PANTHER Pathway | FGF signaling pathway | ||||
| Pathway Interaction Database | FGF signaling pathway | ||||
| Reactome | Activated point mutants of FGFR2 | ||||
| WikiPathways | Regulation of Actin Cytoskeleton | ||||
| Ectoderm Differentiation | |||||
| Hair Follicle Development: Organogenesis (Part 2 of 3) | |||||
| Hair Follicle Development: Induction (Part 1 of 3) | |||||
| Cardiac Hypertrophic Response | |||||
| Signaling Pathways in Glioblastoma | |||||
| Neural Crest Differentiation | |||||
| Signaling by FGFR | |||||
| MicroRNAs in cardiomyocyte hypertrophy | |||||
| Angiogenesis | |||||
| References | |||||
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