| Drug General Information |
| Drug ID |
D0I8WD
|
| Former ID |
DNC002461
|
| Drug Name |
Methyl L-phenylalaninate
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C10H13NO2
|
| Canonical SMILES |
COC(=O)C(CC1=CC=CC=C1)N
|
| InChI |
1S/C10H13NO2/c1-13-10(12)9(11)7-8-5-3-2-4-6-8/h2-6,9H,7,11H2,1H3
|
| InChIKey |
VSDUZFOSJDMAFZ-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
481245, 5239340, 8197495, 15171299, 43131472, 57672908, 76137183, 88834376, 93638556, 103844806, 104362455, 108205896, 117481395, 117481435, 117481436, 125324461, 125702390, 125822192, 126553491, 126759227, 129519305, 135042584, 142391757, 144025602, 152137105, 162101612, 162794897, 167797858, 170505560, 184672969, 218605135, 223109762, 223652068, 223971553, 226454640, 249952210, 251878758
|
| Target and Pathway |
| Target(s) |
Coagulation factor IIa |
Target Info |
Inhibitor |
[1]
|
|---|
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KEGG Pathway
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Neuroactive ligand-receptor interaction
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Complement and coagulation cascades
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Regulation of actin cytoskeleton
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NetPath Pathway
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TCR Signaling Pathway
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PANTHER Pathway
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Blood coagulation
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Pathway Interaction Database
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Thrombin/protease-activated receptor (PAR) pathway
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Angiopoietin receptor Tie2-mediated signaling
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FOXA2 and FOXA3 transcription factor networks
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PAR4-mediated thrombin signaling events
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Syndecan-4-mediated signaling events
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PAR1-mediated thrombin signaling events
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PathWhiz Pathway
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Vitamin K Metabolism
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|
Coagulation
|
|
Reactome
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Intrinsic Pathway of Fibrin Clot Formation
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Common Pathway of Fibrin Clot Formation
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Gamma-carboxylation of protein precursors
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Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
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Removal of aminoterminal propeptides from gamma-carboxylated proteins
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Cell surface interactions at the vascular wall
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Peptide ligand-binding receptors
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Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
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G alpha (q) signalling events
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Thrombin signalling through proteinase activated receptors (PARs)
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WikiPathways
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Complement and Coagulation Cascades
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Regulation of Actin Cytoskeleton
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IL1 and megakaryotyces in obesity
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Regulation of Insulin-like Growth Factor (IGF) Transport and Uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
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PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
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Blood Clotting Cascade
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Gastrin-CREB signalling pathway via PKC and MAPK
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Thrombin signalling through proteinase activated receptors (PARs)
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Platelet Aggregation (Plug Formation)
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GPCR ligand binding
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GPCR downstream signaling
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Formation of Fibrin Clot (Clotting Cascade)
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Cell surface interactions at the vascular wall
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Folate Metabolism
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Vitamin B12 Metabolism
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Selenium Micronutrient Network
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| References |
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
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