Drug General Information
Drug ID
D0I3IZ
Former ID
DNC007754
Drug Name
(2-(4-chlorobenzyloxy)-5-bromophenyl)methanamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528689]
Structure
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2D MOL

3D MOL

Formula
C14H13BrClNO
Canonical SMILES
C1=CC(=CC=C1COC2=C(C=C(C=C2)Br)CN)Cl
InChI
1S/C14H13BrClNO/c15-12-3-6-14(11(7-12)8-17)18-9-10-1-4-13(16)5-2-10/h1-7H,8-9,17H2
InChIKey
YKPADUDRSOXMQB-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) C-C chemokinereceptor type 5 Target Info Inhibitor [528689]
KEGG Pathway Cytokine-cytokine receptor interaction
Chemokine signaling pathway
Endocytosis
Toxoplasmosis
Viral carcinogenesis
NetPath Pathway TSLP Signaling Pathway
TCR Signaling Pathway
IL2 Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database IL12-mediated signaling events
Reactome Binding and entry of HIV virion
Chemokine receptors bind chemokines
G alpha (i) signalling events
WikiPathways TCR Signaling Pathway
GPCRs, Class A Rhodopsin-like
HIV Life Cycle
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 528689Bioorg Med Chem Lett. 2007 Apr 1;17(7):1883-7. Epub 2007 Jan 25.CCR5 receptor antagonists: discovery and SAR of novel 4-hydroxypiperidine derivatives.
Ref 528689Bioorg Med Chem Lett. 2007 Apr 1;17(7):1883-7. Epub 2007 Jan 25.CCR5 receptor antagonists: discovery and SAR of novel 4-hydroxypiperidine derivatives.

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