Drug Information

Drug General Information
Drug ID
D0HQ1W
Former ID
DIB011501
Drug Name
SKF-96365
Drug Type
Small molecular drug
Indication Angina pectoris [ICD9: 413; ICD10:I20] Terminated [539569], [544629]
Company
SmithKline Beecham plc
Structure
Download
2D MOL

3D MOL
Formula
C22H26N2O3
InChI
InChI=1S/C22H26N2O3/c1-25-20-9-5-18(6-10-20)4-3-15-27-22(16-24-14-13-23-17-24)19-7-11-21(26-2)12-8-19/h5-14,17,22H,3-4,15-16H2,1-2H3
InChIKey
HLMBXBGDBBCYII-UHFFFAOYSA-N
CAS Number
CAS 130495-35-1
PubChem Compound ID
104956
PubChem Substance ID
6319097, 10233695, 11120287, 11120775, 11121263, 11121542, 11122022, 11362611, 11365173, 11367735, 11370493, 11370494, 11373336, 11375897, 15052667, 26752097, 26752098, 44434516, 48034870, 48334240, 48334241, 49689237, 50104751, 79562942, 85788250, 92309893, 99300807, 99302325, 103567179, 104373304, 125335472, 128077959, 134345536, 135651058, 139283035, 227010753, 252455617
Target and Pathway
Target(s) Calcium channel Target Info Modulator [531001]
References
Ref 539569(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2441).
Ref 544629Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000362)
Ref 531001The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels. Br J Pharmacol. 2010 Jul;160(6):1464-75.

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