Drug Information

Drug General Information
Drug ID
D0H9RD
Former ID
DIB016986
Drug Name
DZ-2640
Synonyms
(1R,5S,6S)-2-[6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-6(S)-ylsulfanyl]-6-[1(R)-hydroxyethyl]-1-methyl-1-carba-2-penem-3-carboxylic acid pivaloyloxymethyl ester
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Phase 1 [525696]
Structure
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2D MOL

3D MOL
Target and Pathway
Target(s) Bacterial penicillin binding protein Target Info Modulator [525819]
References
Ref 525696Pharmacokinetics and safety of ascending single doses of DZ-2640, a new oral carbapenem antibiotic, administered to healthy Japanese subjects. Antimicrob Agents Chemother. 2000 Mar;44(3):578-82.
Ref 525819In vitro activity of DU-6681a, an active form of the new oral carbapenem compound DZ-2640, in comparison with that of R-95867, faropenem and oral cephalosporins. J Antimicrob Chemother. 2000 Jul;46(1):101-8.

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