TTD | Drug: D0H6DZ

Drug General Information
Drug ID	D0H6DZ
Former ID	DIB020606
Drug Name	OMPT
Synonyms	(2S)-OMPT
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539929]
Structure		Download 2D MOL
Formula	C22H43O6PS
InChI	InChI=1S/C22H43O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)27-19-21(26-2)20-28-29(24,25)30/h10-11,21H,3-9,12-20H2,1-2H3,(H2,24,25,30)/b11-10-/t21-/m0/s1
InChIKey	FCVJYKICQNLXAX-XPTLAUCJSA-N
PubChem Compound ID	16078994
PubChem Substance ID	29217612, 29962715, 135650759, 135689794, 242203384
Target and Pathway
Target(s)	Lysophosphatidate-3 receptor	Target Info	Agonist	[526525]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	PI3K-Akt signaling pathway
	Pathways in cancer
Pathway Interaction Database	LPA receptor mediated events
Reactome	G alpha (q) signalling events
	G alpha (i) signalling events
	Lysosphingolipid and LPA receptors
WikiPathways	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539929	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2912).
Ref 526525	Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor. J Biol Chem. 2003 Apr 4;278(14):11962-9. Epub 2003 Jan 27.

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Drug Information