Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0H4GQ
|
||||
| Former ID |
DNC003544
|
||||
| Drug Name |
RY-066
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [534718] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C21H23N3O3Si
|
||||
| Canonical SMILES |
CCOC(=O)C1=C2C3CCN3C(=O)C4=C(N2C=N1)C=CC(=C4)C#C[Si](C)<br />(C)C
|
||||
| InChI |
1S/C21H23N3O3Si/c1-5-27-21(26)18-19-17-8-10-23(17)20(25)15-12-14(9-11-28(2,3)4)6-7-16(15)24(19)13-22-18/h6-7,12-13,17H,5,8,10H2,1-4H3/t17-/m0/s1
|
||||
| InChIKey |
SNBBNIBMHQGUBE-KRWDZBQOSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Gamma-aminobutyric-acid receptor alpha-3 subunit | Target Info | Inhibitor | [534718] | |
| Gamma-aminobutyric acid receptor | Target Info | Inhibitor | [534718] | ||
| Gamma-aminobutyric acid receptor subunit gamma-2 | Target Info | Inhibitor | [534718] | ||
| Gamma-aminobutyric-acid receptor alpha-2 subunit | Target Info | Inhibitor | [534718] | ||
| Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Inhibitor | [534718] | ||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
| Iron uptake and transportWP706:SIDS Susceptibility Pathways | |||||
| Iron uptake and transport | |||||
| References | |||||
| Ref 534718 | J Med Chem. 1998 Oct 8;41(21):4130-42.Predictive models for GABAA/benzodiazepine receptor subtypes: studies of quantitative structure-activity relationships for imidazobenzodiazepines at five recombinant GABAA/benzodiazepine receptor subtypes [alphaxbeta3gamma2 (x = 1-3, 5, and 6)] via comparative molecular field analysis. | ||||
| Ref 534718 | J Med Chem. 1998 Oct 8;41(21):4130-42.Predictive models for GABAA/benzodiazepine receptor subtypes: studies of quantitative structure-activity relationships for imidazobenzodiazepines at five recombinant GABAA/benzodiazepine receptor subtypes [alphaxbeta3gamma2 (x = 1-3, 5, and 6)] via comparative molecular field analysis. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.