Drug Information

Drug General Information
Drug ID
D0H2HC
Former ID
DIB018092
Drug Name
(R/S) EF-1500
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467822]
Structure
Download
2D MOL
Formula
C21H24N2O2S2
InChI
InChI=1S/C21H24N2O2S2/c1-13-8-11-26-19(13)15(20-14(2)9-12-27-20)5-4-10-22-16-6-3-7-17-18(16)21(24)23-25-17/h5,8-9,11-12,16,22H,3-4,6-7,10H2,1-2H3,(H,23,24)
InChIKey
TYXWOLAOXRISSO-UHFFFAOYSA-N
PubChem Compound ID
53319290
PubChem Substance ID
124961362, 178101304
Target and Pathway
Target(s) Sodium- and chloride-dependent GABA transporter 1 Target Info Inhibitor [543977]
BGT1 Target Info Inhibitor [543978]
KEGG Pathway GABAergic synapse
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
References
Ref 467822(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4583).
Ref 543977(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 929).
Ref 543978(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 932).

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