Drug Information

Drug General Information
Drug ID
D0H2DN
Former ID
DIB012101
Drug Name
DE-310
Synonyms
Exatecan prodrug, Daiichi
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Discontinued in Phase 1 [547221]
Company
Daiichi Seiyaku Co Ltd
Target and Pathway
Target(s) Toposisomerase-1 Target Info Inhibitor [527636]
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway DNA replication
Pathway Interaction Database Caspase Cascade in Apoptosis
WikiPathways Integrated Pancreatic Cancer Pathway
References
Ref 547221Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014192)
Ref 527636DE-310, a macromolecular prodrug of the topoisomerase-I-inhibitor exatecan (DX-8951), in patients with operable solid tumors. Invest New Drugs. 2005 Aug;23(4):339-47.

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