Drug Information
Drug General Information | |||||
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Drug ID |
D0H0AO
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Former ID |
DNC010350
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Drug Name |
Phenyl 7-methoxy-4-phenylbenzofuran-2-ylcarbamate
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C22H17NO4
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Canonical SMILES |
COC1=C2C(=C(C=C1)C3=CC=CC=C3)C=C(O2)NC(=O)OC4=CC=CC=C4
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InChI |
1S/C22H17NO4/c1-25-19-13-12-17(15-8-4-2-5-9-15)18-14-20(27-21(18)19)23-22(24)26-16-10-6-3-7-11-16/h2-14H,1H3,(H,23,24)
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InChIKey |
LJHDOOYWZIWTJW-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Adenosine A2a receptor | Target Info | Inhibitor | [1] | |
KEGG Pathway | Rap1 signaling pathway | ||||
Calcium signaling pathway | |||||
cAMP signaling pathway | |||||
Neuroactive ligand-receptor interaction | |||||
Vascular smooth muscle contraction | |||||
Parkinson's disease | |||||
Alcoholism | |||||
Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
PathWhiz Pathway | Intracellular Signalling Through Adenosine Receptor A2a and Adenosine | ||||
Reactome | NGF-independant TRKA activation | ||||
Adenosine P1 receptors | |||||
G alpha (s) signalling events | |||||
Surfactant metabolism | |||||
WikiPathways | Nucleotide GPCRs | ||||
Monoamine Transport | |||||
GPCRs, Class A Rhodopsin-like | |||||
NGF signalling via TRKA from the plasma membrane | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
GPCRs, Other | |||||
References | |||||
REF 1 | Bioorg Med Chem Lett. 2010 Feb 1;20(3):1090-3. Epub 2009 Dec 11.Synthetic studies on selective adenosine A2A receptor antagonists: synthesis and structure-activity relationships of novel benzofuran derivatives. | ||||
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