Drug Information
Drug General Information | |||||
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Drug ID |
D0G6AQ
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Former ID |
DIB018517
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Drug Name |
2-(3-bromophenyl)histamine
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [538705] | ||
Structure |
Download2D MOL |
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Formula |
C11H12BrN3
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InChI |
InChI=1S/C11H12BrN3/c12-9-3-1-2-8(6-9)11-14-7-10(15-11)4-5-13/h1-3,6-7H,4-5,13H2,(H,14,15)
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InChIKey |
VSKJPAMQPJDPLL-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Histamine H1 receptor | Target Info | Agonist | [526569] | |
Histamine H4 receptor | Target Info | Agonist | [527589] | ||
PANTHER Pathway | Histamine H1 receptor mediated signaling pathway | ||||
References | |||||
Ref 526569 | Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor. J Pharmacol Exp Ther. 2003 Jun;305(3):1104-15. Epub 2003 Mar 6. | ||||
Ref 527589 | Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. J Pharmacol Exp Ther. 2005 Sep;314(3):1310-21. Epub 2005 Jun 9. |
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