TTD | Drug: D0G2AK

Drug General Information
Drug ID	D0G2AK
Former ID	DNC007097
Drug Name	3-methoxy-N',2-diphenylquinoline-4-carbohydrazide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528420]
Structure		Download 2D MOL 3D MOL
Formula	C23H19N3O2
Canonical SMILES	COC1=C(C2=CC=CC=C2N=C1C3=CC=CC=C3)C(=O)NNC4=CC=CC=C4
InChI	1S/C23H19N3O2/c1-28-22-20(23(27)26-25-17-12-6-3-7-13-17)18-14-8-9-15-19(18)24-21(22)16-10-4-2-5-11-16/h2-15,25H,1H3,(H,26,27)
InChIKey	WQHSKTAHWLQAGK-UHFFFAOYSA-N
PubChem Compound ID	44419758
Target and Pathway
Target(s)	Nigral tachykinin NK(3) receptor	Target Info	Inhibitor	[528420]
KEGG Pathway	Calcium signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	G alpha (q) signalling events
WikiPathways	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528420	Bioorg Med Chem Lett. 2006 Nov 15;16(22):5748-51. Epub 2006 Sep 6.N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists.
Ref 528420	Bioorg Med Chem Lett. 2006 Nov 15;16(22):5748-51. Epub 2006 Sep 6.N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information