Drug Information
Drug General Information | |||||
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Drug ID |
D0FJ9W
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Former ID |
DIB016717
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Drug Name |
KB-004
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Synonyms |
Anti-EphA3 tyrosine kinase receptor monoclonal antibody (Humaneered, iv, cancer), KaloBios
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Drug Type |
Antibody
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Indication | Hematological malignancies [ICD9: 200-209; ICD10:C81-C86] | Phase 1/2 | [1] | ||
Company |
KaloBios Pharmaceuticals Inc
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Target and Pathway | |||||
Target(s) | Epha3 tyrosine kinase receptor | Target Info | [2] | ||
KEGG Pathway | Axon guidance | ||||
Pathway Interaction Database | EphrinA-EPHA pathway | ||||
EPHA forward signaling | |||||
Reactome | EPH-Ephrin signaling | ||||
EPHA-mediated growth cone collapse | |||||
EPH-ephrin mediated repulsion of cells | |||||
WikiPathways | NRF2 pathway | ||||
References | |||||
REF 1 | ClinicalTrials.gov (NCT01211691) Study of KB004 in Subjects With Hematologic Malignancies (Myelodysplastic Syndrome, MDS, Myelofibrosis, MF). U.S. National Institutes of Health. | ||||
REF 2 | Clinical pipeline report, company report or official report of Kalobios. | ||||
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