Drug General Information
Drug ID
D0FC4Y
Former ID
DIB019442
Drug Name
compound 31
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526087], [532008]
Structure
Download
2D MOL
Formula
C23H23N7O2S
InChI
InChI=1S/C23H23N7O2S/c1-5-25-22(31)30-23-27-12-19(33-23)16-10-17(20-13(2)8-15(32-4)9-14(20)3)29-21(28-16)18-11-24-6-7-26-18/h6-12H,5H2,1-4H3,(H2,25,27,30,31)
InChIKey
WUCYRTXFXRZKSV-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) testis-specific kinase 1 Target Info Inhibitor [532008]
LIM domain kinase 2 Target Info Inhibitor [532008]
testis-specific kinase 2 Target Info Inhibitor [532008]
LIM domain kinase 1 Target Info Inhibitor [532008]
References
Ref 526087Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells. J Biol Chem. 2001 Aug 17;276(33):31449-58. Epub2001 Jun 19.
Ref 532008Modulation of cofilin phosphorylation by inhibition of the Lim family kinases. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5995-8.
Ref 532008Modulation of cofilin phosphorylation by inhibition of the Lim family kinases. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5995-8.

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