Drug Information

Drug General Information
Drug ID
D0F8VH
Former ID
DIB013272
Drug Name
AA-166
Synonyms
BMP agonist (cartilage repair), Thrasos Therapeutics
Indication Articular cartilage disorders [ICD10:M24.10] Investigative [543483]
Company
Thrasos Therapeutics Inc
Target and Pathway
Target(s) Bone morphogenetic protein receptor Target Info Agonist [543483]
KEGG Pathway Cytokine-cytokine receptor interaction
TGF-beta signaling pathway
Hippo signaling pathway
Signaling pathways regulating pluripotency of stem cells
WikiPathways Endochondral Ossification
Ectoderm Differentiation
Mesodermal Commitment Pathway
Endoderm Differentiation
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Hair Follicle Development: Induction (Part 1 of 3)
Signaling by BMP
Integrated Breast Cancer Pathway
Heart Development
BMP Signalling and Regulation
References
Ref 543483(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1794).
Ref 543483(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1794).

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