Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0F6WW
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| Former ID |
DIB014592
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| Drug Name |
LU-AA33810
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| Synonyms |
LU-AA33810; LU-AE00654; Neuropeptide Y receptor subtype Y5 antagonists (depression); NPY5 antagonists (depression), Lundbeck; Neuropeptide Y receptor subtype Y5 antagonists (depression), Lundbeck
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| Indication | Major depressive disorder [ICD9: 296.2, 296.3, 710.0; ICD10:F32, F33, M32] | Investigative | [1] | ||
| Company |
H Lundbeck A/S
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| Structure |
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Download2D MOL |
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| Canonical SMILES |
O=S(=O)(C)NC[C@H]1CC[C@@H](CC1)Nc1sc2c(n1)c1c(SCC2)cccc<br />1
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| Target and Pathway | |||||
| Target(s) | Neuropeptide Y receptor 5 | Target Info | Antagonist | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 308). | ||||
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