Drug Information

Drug General Information
Drug ID
D0F4QV
Former ID
DIB012162
Drug Name
GSK2696273
Indication Chronic pain [ICD9: 338.2,780; ICD10:R52.1-R52.2, G89] Preregistration [549202]
Company
Glaxosmithkline; molmed
Target and Pathway
Target(s) Adenosine deaminase Target Info Modulator [551928]
BioCyc Pathway Purine nucleotides degradation
Purine deoxyribonucleosides degradation
Purine ribonucleosides degradation to ribose-1-phosphate
Adenosine nucleotides degradation
Superpathway of purine nucleotide salvage
Adenine and adenosine salvage III
KEGG Pathway Purine metabolism
Metabolic pathways
Primary immunodeficiency
NetPath Pathway TCR Signaling Pathway
IL2 Signaling Pathway
PANTHER Pathway Adenine and hypoxanthine salvage pathway
Pathway Interaction Database p73 transcription factor network
C-MYB transcription factor network
Validated transcriptional targets of deltaNp63 isoforms
Validated transcriptional targets of TAp63 isoforms
PathWhiz Pathway Purine Metabolism
Reactome Purine salvage
WikiPathways Metabolism of nucleotides
References
Ref 549202Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033647)
Ref 551928Clinical pipeline report, company report or official report of GlaxoSmithKline.

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