Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0F1WX
|
||||
Former ID |
DNC001378
|
||||
Drug Name |
SSR240600
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Urinary incontinence [ICD9: 788.3; ICD10:N39.3, N39.4, R32] | Phase 2 | [521692] | ||
Structure |
Download2D MOL |
||||
Formula |
C31H35Cl2F6N3O3
|
||||
Canonical SMILES |
CC(C)(C1CCN(CC1)CCC2(CN(CCO2)C(=O)CC3=CC(=CC(=C3)C(F)(F<br />)F)C(F)(F)F)C4=CC(=C(C=C4)Cl)Cl)C(=O)N
|
||||
InChI |
1S/C31H35Cl2F6N3O3/c1-28(2,27(40)44)20-5-8-41(9-6-20)10-7-29(21-3-4-24(32)25(33)17-21)18-42(11-12-45-29)26(43)15-19-13-22(30(34,35)36)16-23(14-19)31(37,38)39/h3-4,13-14,16-17,20H,5-12,15,18H2,1-2H3,(H2,40,44)
|
||||
InChIKey |
ZLNYUCXXSDDIFU-UHFFFAOYSA-N
|
||||
CAS Number |
CAS 537034-22-3
|
||||
PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Substance-P receptor | Target Info | Antagonist | [535610] | |
PANTHER Pathway | CCKR signaling map ST | ||||
Reactome | G alpha (q) signalling events | ||||
References | |||||
Ref 535610 | SSR240600 [(R)-2-(1-[2-[4-[2-[3,5-bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)-2-morpholinyl]ethyl]- 4-piperidinyl)-2-methylpropanamide], a centrally active nonpeptide antagonist of the tachykinin neurokinin-1 receptor: I. biochemical and pharmacological characterization. J Pharmacol Exp Ther. 2002 Dec;303(3):1171-9. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.