Drug Information
Drug General Information | |||||
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Drug ID |
D0F0IA
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Former ID |
DNC000124
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Drug Name |
A-381393
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [543137] | ||
Structure |
Download2D MOL |
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Formula |
C20H24N4
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InChI |
InChI=1S/C20H24N4/c1-15-7-8-17(13-16(15)2)24-11-9-23(10-12-24)14-20-21-18-5-3-4-6-19(18)22-20/h3-8,13H,9-12,14H2,1-2H3,(H,21,22)
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InChIKey |
SAQMCVDGOIRQTC-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | D(4) dopamine receptor | Target Info | Antagonist | [535158], [536766] | |
References | |||||
Ref 535158 | Comparative molecular field analysis of dopamine D4 receptor antagonists including 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 113), 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]-1H-pyrrolo-[2,3-b]pyridine (L-745,870), and clozapine. J Med Chem. 2001 Apr 12;44(8):1151-7. | ||||
Ref 536766 | Dopamine D4 receptor involvement in the discriminative stimulus effects in rats of LSD, but not the phenethylamine hallucinogen DOI. Psychopharmacology (Berl). 2009 Apr;203(2):265-77. Epub 2008 Jul 6. |
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